Recently, Duke University release their latest research paper of Real-time three-dimensional single-particle tracking (RT-3D-SPT). “With the new galvo-based implementation, notable increases in tracking duration, localization precision, and the degree to which the objects are locked to the center of the detection volume were observed. These results suggest faster control response elements can expand RT-3D-SPT to a broader range of chemical and biological systems. “
The experiment used Sino Galvo high speed galvo scanner SG7220-A to realize approximately five-time faster response rate compared with the previous XY piezoelectric stage. This is because galvo scanning mirror deflects the laser beam to follow the particle with a response time rather than moving the sample.
REFERENCES
(1) https://www.biorxiv.org/content/10.1101/2023.03.28.534562v1.full.pdf+html